|
Chemical structure of edrophoniumEdrophonium is a readily reversible acetylcholinesterase inhibitor. It prevents breakdown of the neurotransmitter acetylcholine and acts mainly at a neuromuscular junction.
Clinical uses
Because its duration of action is single astir X proceedings, edrophonium is utilized to differentiate myasthenic crisis from cholinergic crisis. Around myasthenic crisis, in which the human is non breathe to create plenty neuromuscular stimulation, edrophonium will reduce a muscle weakness. Within the cholinergic crisis, in which the individual has overmuch neuromuscular stimulation, edrophonium will make the muscle weakness worse.
Edrophonium is available under a marque Enlon (AstraZeneca).
Sources
Brenner, G. M. (2000). Pharmacological medicine. Philadelphia, PA: W.B. Saunders Company. ISBN 0-7216-7757-6
Canadian Druggist Association (2000). Compendium of Pharmaceutic & Specialties (Twenty-fifth ed.). Toronto, In: Webcom. ISBN 0-919115-76-4
|